semaglutide glp-1

Semaglutide Dosage & Titration Compared to Tirzepatide

Both semaglutide and tirzepatide are GLP-1 receptor agonists used to treat type 2 diabetes. They work by mimicking the incretin hormone GLP-1, which stimulates insulin production and suppresses glucagon secretion. However, there are some key differences in semaglutide dosage and their titration schedules and potential side effects.

Semaglutide titration:

Tirzepatide titration:

  • Starting dose Tirzepatide: 5 mg once weekly, can be increased to 10 mg once weekly after 4 weeks if needed.
  • Maximum dose: 15 mg once weekly.
  • Titration intervals: 4 weeks.

Potential side effects:

  • Semaglutide: Nausea, vomiting, diarrhea, constipation, abdominal pain, injection site reactions, hypoglycemia (low blood sugar).
  • Tirzepatide: Similar to semaglutide, but may also cause gastroesophageal reflux disease (GERD) and dizziness.

It’s important to note that:

  • The optimal titration schedule for both medications may vary depending on individual factors such as age, weight, kidney function, and response to treatment.
  • Only a doctor can determine the best medication and titration schedule for you. They will take into account your individual needs and medical history.
    It is important to follow your doctor’s instructions carefully and report any side effects you experience.

Here are some additional resources that you may find helpful: